Does he have clinical depression? I know there are some natural things for that like St John's Wort and Sam-E. You need to get a good brand though because cheap brands can be worthless. Go to a health food store or a naturopath to get a good recommendation. Also I believe exercise is recommended for clinical depression foremost.
Norcalgal, I am praying for God to intervene in behalf of your husband and help him to be restored to health emotionally physically and spiritually. In the name of Jesus Christ, amen.
Why is he so depressed? There are treatments for clinical depression. Maybe he needs to see a psychologist. Preferably a Christian one, but really maybe even a secular psychologist could help. What is going on? In the meantime, I heard of a woman who was so depressed she had never gotten out of bed for about 17 years. A Christian counselor gave her a bookmark that changed her life. You can find it at freedominchrist.com It is called the "Who I am in Christ" bookmark. She began reading the Scripture verses and affirmations on that bookmark, and it changed her whole life. She was able to get out of bed and go on with her life and to have one. Maybe you could order that bookmark for your husband.